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Our Services
Assay Development
Helix3 constantly strives to develop and optimize in vitro and in vivo assays aimed at improving human safety while reducing the use of animals in safety testing.

Believing that good science can be both socially responsible and cost-effective, Helix3 provides innovative approaches to help identify potential health hazards in the early stages of development.  We combine our regulatory compliance with scientific problem-solving to help you to optimize your developmental decision tree.

Examples of assays developed and validated by Helix3 and successfully incorporated into our regularly provided GLP laboratory services include:

The in vivo comet assay in multiple tissues

The combined in vivo comet and micronucleus assay

Single cell detection of cytotoxicity in target organs

The DNA reactivity dose response curve assay

Copyright© 2003-2012 Helix3 Inc.  All Rights Reserved
 
U.S. FDA Drug Safety Testing

ICH Safety Guidelines

European REACH Chemical Regulations

EMEA Guidance on Genotoxicity Testing of Medicines

Comet Assay Interest Group

U.S. Environmental Mutagen Society

Genetic Toxicology Association

Important Information