HELIX3

INC.

 

Our Services

GLP Multiple Endpoint Studies

 

 

 

 

 

 

 

 

 

 

 

 

 

In Vitro Protocol Options

(+/- metabolic activation)

 

Micronucleus (MN) and Comet

Chromosome Abberations (CA) and Comet

Acellular Comet

 

In Vivo Protocols Options

 

Chronic Tox and Comet

Subchronic or Acute Tox and Comet

Pharmacokinetics (PK) and Comet

Micronucleus and Comet

Note: Comet can be incorporated into any ongoing study at any test site. Go to Mobile Unit Services for more information.

 

 

 

In response to clients’ needs to reduce the time and expense associated with the development of compounds, Helix3 has developed multiple endpoint protocols combining standard tests with the comet assay.

Incorporating the comet assay in the standard battery of in vitro and in vivo tests (or even early stage research & development) provides the ability to detect multiple classes of damaging agents in the same study using the same test system and exposure conditions. 

And by including the comet assay in the in vitro tests, results are directly comparable to target organ comet data from in vivo studies.